This combination of Mefenamic Acid and Paracetamol in a flavoured syrup base is used for its analgesic and antipyretic effects. Here’s an overview of each component and their combined uses:

Components:

Mefenamic Acid IP (50mg per 5ml syrup):

Description: Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce inflammation, pain, and fever.

Uses:
Pain Relief: Effective for managing mild to moderate pain, such as headaches, menstrual cramps, and musculoskeletal pain.
Anti-Inflammatory: Helps reduce inflammation in conditions like arthritis.
Fever Reduction: Useful in lowering fever.

Paracetamol IP (125mg per 5ml syrup):

Description: Paracetamol (also known as acetaminophen) is an analgesic and antipyretic that helps relieve pain and reduce fever.

Uses:
Pain Relief: Provides relief from mild to moderate pain, including headaches, toothaches, and muscle pain.
Fever Reduction: Effective for lowering fever, especially in children and adults.

Flavoured Syrupy Base:

Description: Added to improve the taste and palatability of the syrup, making it more acceptable, especially for children.

Uses:
Enhances the acceptability of the medication, ensuring better adherence to the prescribed treatment.

Uses of the Combination:

Pain and Fever Management:

Description: This combination is effective in managing pain and reducing fever. It is particularly useful for conditions where both pain and fever are present, such as common colds or mild infections.
Effect: Mefenamic acid provides anti-inflammatory and pain-relieving effects, while paracetamol offers additional pain relief and fever reduction.

Menstrual Pain:

Description: Useful for relieving pain associated with menstrual cramps.
Effect: The combination addresses both pain and associated fever, providing symptomatic relief during menstruation.

Headache and Musculoskeletal Pain:

Description: Effective for treating headaches and pain from minor injuries or musculoskeletal issues.
Effect: Provides both analgesic and anti-inflammatory effects, improving overall comfort and reducing discomfort.

How It Works:

Mefenamic Acid: Inhibits cyclooxygenase (COX) enzymes, reducing the production of prostaglandins that cause pain and inflammation.
Paracetamol: Acts on the central nervous system to alleviate pain and reduce fever, with a mechanism that is less well understood but does not have significant anti-inflammatory properties.

This combination provides effective relief from pain and fever, making it suitable for treating a variety of symptoms in a convenient liquid form.